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Journal of Probability and Statistics
Volume 2012, Article ID 485174, 16 pages
http://dx.doi.org/10.1155/2012/485174
Review Article

Mixed Modeling with Whole Genome Data

MRC Epidemiology Unit & Institute of Metabolic Science, Addrenbrooke's Hospital, Box 285, Hills Road, Cambridge CB2 0QQ, UK

Received 2 March 2012; Accepted 20 April 2012

Academic Editor: Yongzhao Shao

Copyright © 2012 Jing Hua Zhao and Jian'an Luan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The Supplementary Material provides details of the implementation in R and SAS for models described in the paper. Although this is largely done through the GAW17 data, it demonstrates through the Framingham data how to use IBD information output from PLINK. Moreover, it also includes details of simulation under a multivariate model as a motivating example for family data.

  1. Supplementary Material