Mixed Modeling with Whole Genome Data

Table 4

AFFECTED and VEGFC under a Cox model.

Model/parameter	Estimate	SE	𝑧	Integrated/penalized likelihoods^†
Kinship				−998.8/−980.6
𝜎^2𝑃	0.2073
SEX	0.05267	0.1541	0.34
SMOKE	0.5000	0.1622	3.08
Kinship + IBD				−996.1/−967.3
𝜎^2𝑃	0.002690
𝜎^2𝑀	0.3615
SEX	0.07146	0.1603	0.43
SMOKE	0.5560	0.1696	3.28

^†The log likelihood under the null is −1003.9.