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Journal of Probability and Statistics
Volume 2012 (2012), Article ID 527351, 20 pages
Review Article

Methodology and Application of Adaptive and Sequential Approaches in Contemporary Clinical Trials

1Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA 30322, USA
2Winship Cancer Institute, Emory University, 1365-B Clifton Road, Room B4109, Atlanta, GA 30322, USA
3Department of Mathematics and Statistics, Georgia State University, Atlanta, GA 30303, USA

Received 29 June 2012; Revised 8 October 2012; Accepted 9 October 2012

Academic Editor: Xuelin Huang

Copyright © 2012 Zhengjia Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [3 citations]

The following is the list of published articles that have cited the current article.

  • Zhengjia Chen, Ye Cui, Taofeek K. Owonikoko, Zhibo Wang, Zheng Li, Ruiyan Luo, Michael Kutner, Fadlo R. Khuri, and Jeanne Kowalski, “Escalation with Overdose Control using All Toxicities and Time to Event Toxicity Data in Cancer Phase I Clinical Trials,” Contemporary Clinical Trials, 2014. View at Publisher · View at Google Scholar
  • Thomas M. Braun, “The current design of oncology phase I clinical trials: Progressing from algorithms to statistical models,” Chinese Clinical Oncology, vol. 3, no. 1, 2014. View at Publisher · View at Google Scholar
  • El-Sayed M. El-Alfy, “Evaluation of sequential adaptive testing with real-data simulation: A case study,” Journal of Intelligent & Fuzzy Systems, vol. 32, no. 4, pp. 2977–2986, 2017. View at Publisher · View at Google Scholar