Research Article

A Two-Stage Penalized Logistic Regression Approach to Case-Control Genome-Wide Association Studies

Table 2

The simulated average PDR and FDR under Model 1: multiplicative effects both within and between loci.

( 𝑛 , 𝑃 ) 𝜆 𝑞 PDRFDR
TPLR MT TPLR MT

(800,1000)  0.80.1 0.6100.780 0.3580.996
0.90.1 0.8500.900 0.3200.998
1.00.1 0.9601.000 0.2190.999

(800,5000)  0.80.1 0.4700.660 0.4050.999
0.90.1 0.7500.870 0.3800.999
1.00.1 0.8900.930 0.2330.999