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Journal of Sensors
Volume 2011, Article ID 406425, 7 pages
http://dx.doi.org/10.1155/2011/406425
Research Article

A Camera Phone Localised Surface Plasmon Biosensing Platform towards Low-Cost Label-Free Diagnostic Testing

1The Photonic Systems Group, Department of Electrical and Computing Engineering, McGill University, McConnell Building, Montreal, Quebec, Canada H3A 2A7
2Sensor Microsystems Laboratory, Department of Electrical and Computing Engineering, McGill University, McConnell Building, Montreal, Quebec, Canada H3A 2A7

Received 8 August 2011; Revised 28 September 2011; Accepted 29 September 2011

Academic Editor: Jiri Homola

Copyright © 2011 Philip J. R. Roche et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Developmental work towards a camera phone diagnostic platform applying localized surface plasmon resonance (LSPR) label-free sensing is presented. The application of spherical gold nanoparticles and nanorods are considered and assessed against ease of application, sensitivity, and practicality for a sensor for the detection of CCL2 (chemokine ligand 2). The sensitivity of the platform is compared with that of a commercial UV/Vis spectrometer. The sensitivity of the camera phone platform is found to be 30% less than that of the commercial system for an equivalent incubation time, but approaches that of the commercial system as incubation time increases. This suggests that the application of LSPR sensing on a portable camera phone devices may be a highly effective label-free approach for point-of-care use as a low-cost diagnostic sensing tool in environments where dedicated equipment is not available.