Histopathological Variants of Cutaneous Squamous Cell Carcinoma: A Review
Figure 4
Invasive squamous cell carcinoma (SCCI). (a) Well-differentiated lesions show prominent keratinization and may form “pearl-like” structures where dermal nests of keratinocytes attempt to mature in a layered fashion (40x). (b) Moderately differentiated lesions of SCCI show much less organization and maturation with significantly less keratin formation (40x).