Pigmentation, Melanocyte Colonization, and p53 Status in Basal Cell Carcinoma
Figure 1
Correlation of pigmentation with melanocyte colonization (a) and lack of correlation between p53 positivity and melanocyte colonization. (b) 49 BCC tissue sections were analyzed immunohistochemically for the presence of melanin, the expression of the melanocyte marker melan-A and p53 expression. The frequency of melanin- and p53-positive tumor cells as well as the frequency of melan-A-expressing melanocytes was scored. (a) The correlation between melanocytes and pigmentation was statistically significant (). (b) There was no correlation between the frequency of melanocytes and p53 expression ().
