Pigmented Nodular Basal Cell Carcinomas in Differential Diagnosis with Nodular Melanomas: Confocal Microscopy as a Reliable Tool for In Vivo Histologic Diagnosis
Figure 3
(a) Dermoscopic image of nodular pigmented lesion with an atypical globular pattern, structureless dark brown areas, irregular brown dots in the center of the lesion (white arrowhead), and a blue-white veil (original magnification 50). (b) RCM image ( mm) acquired at stratum granulosum-spinosum, showing broadened honeycombed (scale bar: 50 m). (c) RCM image ( mm), at dermal level, showing markedly pleomorphic cells distributed in sheet-like structures in the dermis and numerous bright dots. Inside the tumoral nested proliferation, new-born vessels are present (yellow arrows) (scale bar: 50 m). (d) Histological image showing an overview of the nodular melanoma with Breslow thickness of 6.5 mm (H&E section; original magnification 400).
