Deciphering Squamous Cell Carcinoma Using Multidimensional Genomic Approaches
Figure 5
Genome-wide comparison of lung adenocarcinoma (AC) and squamous cell carcinoma (SqCC). Affymetrix SNP 6.0 data for 11 SqCC and 49 AC cell lines were downloaded from the Wellcome Trust Sanger Cancer Genome Project. Data were analyzed against a pool of a normal reference samples using Partek Genomics Suite. For each position in the genome, the frequency of (a) gain and (b) loss are shown for SqCC (purple) and AC (orange). (c) Magnified view of chromosome arm 8p shows that SqCC has a higher frequency of segmental DNA gain at cumulative position 1.43 Gbp as compared to AC.
