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Figure 1: Curcumin inhibits skin SCC cell growth in vitro and in vivo. (a) Cell proliferation of the aggressive skin cancer cell line SRB12-p9 after treatment with 0–40 μM curcumin. versus control group; versus control group; versus control group. (b) Mice were pretreated with the indicated dose of curcumin for 3 days prior to injection with SRB12-p9 tumor cells in the dorsal region (day 0) and continued receiving daily curcumin treatment (9 mice per group, mean tumor volume ± SD). Tukey’s post hoc test: versus control group; versus control group. (c) Representative images of xenograft tumors at harvest and ex vivo from the indicated treatment groups.