Ultraviolet Radiation and the Slug Transcription Factor Induce Proinflammatory and Immunomodulatory Mediator Expression in Melanocytes

Table 1

Altered expression of proinflammatory and immunomodulatory mediators by normal human melanocytes.

Treatment	Gene	UVR-exposed/unexposed^a	Treatment	Gene	Slug-transduced/control^a
UVR	CCL2	2.50, 6.63	Slug	BLNK	2.99, 2.38
	CXCL1	5.06, 3.80		CCL18	4.77, 3.53
	CXCL2	6.86, 6.53		CXCL10	4.26, 6.03
	CXCL3	10.61, 13.11		FGF10	2.73, 2.77
	IL12A	7.41, 2.21		IFNA4	2.53, 3.13
	IL1RAP	−2.35, −2.07		IFNWP2	2.53, 2.02
	IL20	2.66, 2.79		IL1R2	2.88, 4.21
	IL8	5.92, 10.21		IL20	2.81, 2.70
	NFκB 1	−2.95, −2.61		IL22	2.47, 5.09
	NFX1	−2.54, −2.49		IL4	3.54, 3.04
	NR3C1	−2.80, −2.45		IL5RA	2.49, 4.40
	PTAFR	−3.06, −2.01		MGLL	−2.95, −4.24
	PTGS2	2.93, 2.52		PROCR	2.19, 2.34
	RIPK2	−2.46, −2.25		SERPINF2	2.56, 2.51
	TNFSF9	6.72, 2.86		TACR1	−2.88, −2.92

^aValues for both replicate assays are shown.