Epidemiological Profile of Patients with Cutaneous Melanoma in a Region of Southern Brazil

Table 2

Clinical and histopathological characteristics of patients with cutaneous melanoma in the western region of Santa Catarina, Brazil, classified by gender.

Characteristics (n)	Men	Women	P
Age (497)	50.45±15.20	50.81±15.57	0.045**
Site (489)			<0.001*
Head and neck	36 (17.82)	55 (19.16)
Trunk	73 (36.14)	55 (19.16)
Members	76 (37.62)	164 (57.14)
Unknown	17 (8.42)	13 (4.54)
Histological type (445)			0.04*
SSM	104 (59.10)	183 (68.03)
NM	42 (23.86)	48 (17.84)
LMM	13 (7.39)	20 (7.43)
MAL	8 (4.54)	9 (3.35)
Other	9 (5.11)	9 (3.35)
Tumor thickness (mm) (462)			<0.01*
≤1 mm	73 (39.46)	135 (48.74)
1.01–2.0	29 (15.67)	54 (19.49)
2.01–4.0	28 (15.14)	49 (17.69)
>4.0	55 (29.73)	39 (14.08)
Clark (420)			<0.01*
I	26 (15.76)	29 (11.37)
II	16 (9.70)	42 (16.47)
III	33 (20)	78 (30.59)
IV	72 (43.64)	100 (39.22)
V	18 (10.90)	6 (2.35)
Presence of ulceration (418)			0.013*
Yes	67 (41.61)	78 (30.35)
No	94 (58.39)	179 (69.65)
Presence of regression (399)			0.254*
Yes	37 (24.02)	49 (20.00)
No	117 (75.98)	196 (80.00)
Mitotic index (mitoses/mm^2) (401)			0.045*
0	27 (17.65)	49 (19.76)
≥1	126 (82.35)	199 (80.24)
SLN positive (225)			0.600*
Yes	21 (24.70)	16 (11.42)
No	64 (72.30)	124 (88.57)
Growth phase (434)			0.271*
Radial	28 (16.57)	49 (18.49)
Vertical	141 (83.43)	216 (81.51)
Vascular invasion (400)			0.877*
Yes	16 (10.19)	24 (9.88)
No	141 (89.81)	219 (90.12)
Perineural invasion (392)			0.398*
Yes	6 (3.82)	4 (1.70)
No	151 (96.18)	231 (98.30)

Data presented as mean ± SD and frequency (percentage). **Student’s t-test * Chi-square test. SSM, superficial spreading melanoma; NM, nodular melanoma; LMM, lentigo maligna melanoma; MAL, acrolentiginous melanoma; SLN, sentinel lymph node.