Potential Role of Meiosis Proteins in Melanoma Chromosomal Instability

Table 2

Summary of the differences between meiosis I, meiosis II, and mitosis.

	Meiosis I	Meiosis II	Mitosis
Reductional division	Yes	No	No
Equational division	No	Yes	Yes
Daughter Cells Genetically Identical	No	No	Yes
Double strand breaks introduced by SPO11	Yes	No	No
Pol β required for meiotic recombination and chromosome synapsis	Yes	No	No
Homologous chromosome recombination and segregation	Yes	No	No
Degradation of cohesion along chromosome arms	Yes	Not present	Not present
Degradation of cohesion at centromeres	No	Yes—during anaphase II	Yes—during anaphase
SGO2 protection of REC8 located at pericentromeric regions	Yes	No	No