Clinical Study

Safety and Efficacy of 188-Rhenium-Labeled Antibody to Melanin in Patients with Metastatic Melanoma

Table 3

Radiation-absorbed doses of 188Re-6D2 compared to tositumomab, ibritumomab tiuxetan, and normal organ tolerance TD 5/5 (cGy).

LiverKidneysBone marrowUrine bladder wall

Tositumomab 81 mCi246588195192
Ibritumomab tiuxetan 30 mCi53311144100
188Re-6D2 40–60 mCi13030517158
188Re-6D2 Estimated 100 mCi34465042350
Normal Organ Tolerance300023002006500