Cutaneous Human Papillomavirus Infection and Development of Subsequent Squamous Cell Carcinoma of the Skin

Table 4

Association between cutaneous human papillomavirus (HPV) infection in eyebrow hair and the risk of subsequent squamous cell carcinoma (SCC).

Eyebrow hair viral infection	No subsequent SCC; ()	Subsequent SCC ()	(95% CI)
at the index SCC diagnosis
Any beta
DNA negative	6 (10.5)	12 (13.6)	1.00
DNA positive	51 (89.5)	76 (86.4)	0.84 (0.45–1.56)
Any beta 1
DNA negative	6 (13.6)	12 (16.2)	1.00
DNA positive	38 (86.4)	62 (83.8)	0.84 (0.44–1.58)
Any beta 2
DNA negative	6 (12.0)	12 (16.2)	1.00
DNA positive	44 (88.0)	62 (83.8)	0.85 (0.45–1.59)
Multiple beta 1
DNA negative	25 (56.8)	37 (50.0)	1.00
DNA positive	19 (43.2)	37 (50.0)	1.18 (0.72–1.93)
Multiple beta 2
DNA negative	29 (58.0)	35 (47.3)	1.00
DNA positive	21 (42.0)	39 (52.7)	1.23 (0.75–2.01)

hair DNA positive to any beta HPV type versus negative to all 25 beta HPV types. hair DNA positive to at least one beta 1 HPV type versus DNA negative to 25 beta HPV types. hair DNA positive to at least one beta 2 HPV type versus DNA negative to 25 beta HPV types. hair DNA positive to 2 or more beta-1 HPV types versus DNA negative to 25 beta HPV types or positive to one beta 1 HPV type. hair DNA positive to 2 or more beta 2 HPV types versus DNA negative to 25 beta HPV types or positive to one beta 2 HPV type. HR = hazards ratio, CI = confidence interval. for age and gender.