Journal of Skin Cancer

Merkel Cell Carcinoma of the Head and Neck: Challenges in Diagnosis and Therapy


Publishing date
15 Feb 2013
Status
Published
Submission deadline
28 Sep 2012

Lead Editor

1Department of Otolaryngology—Head and Neck Surgery, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, Austria

2Department of Otolaryngology—Head and Neck Surgery, Mount Sinai School of Medicine, One Gustave L. Levy Place Box 1189, New York, NY 10029, USA

3Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, Canada M4N 3M5


Merkel Cell Carcinoma of the Head and Neck: Challenges in Diagnosis and Therapy

Description

Merkel cell carcinoma is a rare and highly aggressive malignant tumor of the skin with a high predilection for regional lymph node involvement, distant metastases, and local recurrence. The US Surveillance Epidemiology and End Results Program (SEER database) estimated an incidence of 0.32 per 100.000 people and approximately 45–48% of all primary tumours appear in the head and neck region. Recent advances in biology and medicine have introduced new technologies to study the genetics of Merkel cell carcinoma and the mechanisms underlying its pathology. Knowledge and understanding of these conditions have led to the development of new diagnostic tests, successful therapies, and novel tools to characterize these clinical conditions and provide better care to patients.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the carcinogenesis of Merkel cell carcinoma, the development of strategies to treat these patients, and the evaluation of outcomes. Potential topics include, but are not limited to:

  • Recent epidemiologic data
  • New insights into molecular mechanisms of MCPyV
  • Latest diagnostic, prognostic, and target proteins in Merkel cell carcinoma
  • Role of inflammation in Merkel cell carcinoma
  • Surgical management of Merkel cell carcinoma
  • Role of radiation therapy
  • Chemotherapy in metastatic disease
  • Epidemiological data on Merkel cell carcinoma in relation to sun exposure
  • Advances in molecular genetics and molecular diagnostics
  • Current concepts in the treatment of Merkel cell carcinoma using Mohs surgery, ablative approaches, and microvascular reconstruction
  • Role of radiotherapy in the node negative patient
  • New concepts for chemotherapy in patients with metastatic disease

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jsc/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 427984
  • - Editorial

Merkel Cell Carcinoma of the Head and Neck: Challenges in Diagnosis and Therapy

Brett A. Miles
  • Special Issue
  • - Volume 2013
  • - Article ID 929364
  • - Review Article

Merkel Cell Carcinoma: The Past, the Present, and the Future

Inamaria Erovic | Boban M. Erovic
  • Special Issue
  • - Volume 2013
  • - Article ID 327150
  • - Review Article

Merkel Cell Carcinoma: Chemotherapy and Emerging New Therapeutic Options

Laura Desch | Rainer Kunstfeld
  • Special Issue
  • - Volume 2013
  • - Article ID 973123
  • - Review Article

Imaging in Patients with Merkel Cell Carcinoma

Elisabeth Enzenhofer | Philipp Ubl | ... | Boban M. Erovic
  • Special Issue
  • - Volume 2013
  • - Article ID 189342
  • - Review Article

Merkel Cell Carcinoma: Interdisciplinary Management of a Rare Disease

Sven Schneider | Dietmar Thurnher | Boban M. Erovic
  • Special Issue
  • - Volume 2013
  • - Article ID 325086
  • - Research Article

Merkel Cell Carcinoma of the Head and Neck: A Single Institutional Experience

G. Morand | D. Vital | ... | G. F. Huber
  • Special Issue
  • - Volume 2012
  • - Article ID 680410
  • - Review Article

Which Are the Cells of Origin in Merkel Cell Carcinoma?

Thomas Tilling | Ingrid Moll
  • Special Issue
  • - Volume 2012
  • - Article ID 563829
  • - Review Article

A Review of Radiotherapy for Merkel Cell Carcinoma of the Head and Neck

Justin Lee | Ian Poon | ... | Elizabeth Barnes
  • Special Issue
  • - Volume 2012
  • - Article ID 176173
  • - Review Article

Role of Sentinel Lymph Node Biopsy in the Management of Merkel Cell Carcinoma

Eric P. Arruda | Kevin M. Higgins
  • Special Issue
  • - Volume 2012
  • - Article ID 742303
  • - Review Article

The Role of Free Tissue Transfer in Merkel Cell Carcinoma of the Head and Neck

Aldo V. Londino III | Brett A. Miles
Journal of Skin Cancer
 Journal metrics
Acceptance rate29%
Submission to final decision34 days
Acceptance to publication25 days
CiteScore2.100
Impact Factor-
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