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New Treatment Modalities to Heal Facial Malignancies

Call for Papers

Skin cancers are the most common and the most preventable form of cancers. An estimated 5.4 million cases of cutaneous basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are diagnosed every year in the United States. Currently the surgical treatment of extraorally located benign or malignant tumors of the facial skin involves tumor resection and defect reconstruction with either free skin grafts or regional flaps, which are moved to the defect by means of various flap mobilization techniques.

Facial reconstructive surgery aims to reestablish a “normal” face as closely as possible. In anatomic and aesthetic sense, a face is mainly divided into central and peripheral units. Both of these units topographically involve several facial aesthetic units and subunits that are constituted according to skin quality, thickness, color, texture, and contour. The central unit involves nose, lip, and eyelid; the peripheral unit involves cheek and forehead. All surgical techniques are associated with mobilization of neighboring soft tissue in order to achieve tension-free wound closure. Accordingly, in relation to the defect size large incision and mobilization of the neighboring soft tissue are needed in many cases. The latter contributes to large skin wounds, associated with the risk of damaging other important tissues for facial function, such as vessels and nerves.

There are some regions in the face, such as the nose and forehead, where skin tissue mobilization for flap extent is compromised. Consequently, the dangers of raising the flap are increased. Thus, techniques to reduce the amount of mobilization to a minimum and at the same time permit tension-free closing of the wound are of high interest to reduce morbidity of such surgical interventions. Aesthetic considerations are also justified in the face, because larger incisions bear the risk of greater visibility.

Reconstruction of every facial unit is a challenge and should be tailored according to the following factors: defect related (size, shape, location, and thickness); patient related (comorbidities, habits expectancies, etc.); surgeon related (experience) ones.

The aim of present special issue is to publish research articles whose visualizations will be at the forefront on the reconstruction of facial defects.

Potential topics include but are not limited to the following:

  • Facial skin cancers: classification and clinical characteristics
  • Nonmelanoma skin tumors
  • Melanoma in the facial region
  • Dermal metastases in squamous cell carcinomas of the facial regions
  • Medical treatment for facial skin cancer prior to the surgery: in the view of dermatologists
  • Minimally invasive surgery in facial tumors
  • Which treatment modalities should be applied in facial skin cancers: surgery, chemotherapy, or radiotherapy
  • Sentinel lymph node and prognosis in facial malignancies
  • Reconstruction for facial skin tumors
    • Reconstructive outcomes of Mohs surgery
    • Reconstruction of large facial defects after delayed Mohs surgery
    • Skin and composite grafting techniques in facial reconstruction for skin cancer
    • Nasolabial and forehead flap reconstruction of nasal alar and upper lip defects
    • Rare facial malignant tumors and reconstruction
    • Locally advanced cheek carcinomas, radical surgeries, and reconstruction
    • Functional and aesthetic outcome of reconstruction of large orofacial defects
    • Orbital exenteration for invasive skin tumors

Authors can submit their manuscripts through the Manuscript Tracking System at

Submission DeadlineFriday, 23 March 2018
Publication DateAugust 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

Lead Guest Editor

  • Fatih Oghan, Kutahya Dumlupinar University, Kutahya, Turkey

Guest Editors