Statins Attenuate the Increase in P-Selectin Produced by Prolonged Exercise
Table 1
Subject characteristics.
Variable
Statin ( = 37)
Control ( = 43)
Age (years)
56 ± 8
51 ± 7*
Resting systolic blood pressure (mmHg)
140 ± 16
137 ± 17
Resting diastolic blood pressure (mmHg)
78 ± 15
78 ± 11
Body mass index (kg/m2)
23.6 ± 2.5
23.1 ± 2.9
Low-density lipoprotein cholesterol (mg/dL)
87 ± 26
104 ± 24*
High-density lipoprotein cholesterol (mg/dL)
65 ± 14
74 ± 21*
Baseline p-selectin
52.6 ± 20.8
54.7 ± 21.7
Training mileage (miles/week)
37 ± 19
40 ± 13
Taper mileage (miles/week)
22 ± 16
19 ± 11
Official finishing time (hr:min)
4:15 ± 0:47
3:58 ± 0:41
Blood pressure medication use
= 9
= 2
Vitamin/supplement use
= 12
= 14
Training mileage = average miles run per week during training for the Boston Marathon; Taper mileage = miles run in the week preceding the marathon. ; statin versus control.
