Review Article

Interactions of Gut Microbiota, Endotoxemia, Immune Function, and Diet in Exertional Heatstroke

Table 1

Predisposing factors for exertional heatstroke.

Hot, humid environment with direct solar radiation and little wind movement
Insulated clothing
Low ratio of skin surface area to body mass
Recent (1ā€“3 days) stressful heat exposure
Lack of heat acclimatization
Medications that alter sweat gland function, cutaneous vasoconstriction, or cardiac contractility
Skin disorders (e.g., ectodermal dysplasia, burns, anhidrosis)
Strenuous or prolonged exercise
Overweight, obesity
Dehydration
Diarrhea, vomiting
Use of diuretics and laxatives
Fever and illness
Infectious disease
Low cardiorespiratory physical fitness
Alcohol abuse or drug use
Older age
Sleep deprivation

Sources. [1ā€“3, 50, 164, 322].