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Volume 18, Issue 2, Pages 155-159

Recent developments in Raman and infrared spectroscopy and imaging of bone tissue

Michael D. Morris and William F. Finney

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA

Copyright © 2004 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Vibrational spectroscopy is an important tool in mineralized tissue research. This review focuses on recent applications of Raman and IR spectroscopies as contrast enhancement agents, tools for studying the chemical nature of changes in bone tissue with age and disease and understanding the molecular nature of changes in bone tissue during mechanical loading and fracture.