Raman spectroscopic study of photosensitive damage to lysozyme structure sensitized by hypocrellin A

Zhou, J. H.; Wu, X. H.; Wei, S. H.; Gu, X. T.; Feng, Y. Y.; Wang, X. S.; Zhang, B. W.

doi:https://doi.org/10.1155/2006/152816

Journal of Spectroscopy

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Volume 20 | Article ID 152816 | https://doi.org/10.1155/2006/152816

Raman spectroscopic study of photosensitive damage to lysozyme structure sensitized by hypocrellin A

J. H. Zhou,^1,3X. H. Wu,¹S. H. Wei,¹X. T. Gu,¹Y. Y. Feng,¹X. S. Wang,²and B. W. Zhang²

Abstract

Laser Raman spectroscopy was used to detect the nature of the structural change in lysozyme sensitized by hypocrellin A (HA) at the molecular level. The results indicated that the orderly structure of lysozyme has been damaged by the active oxygen (¹O₂, O₂^−· and .OH, etc.) generated by HA, and cause the changes in H-bonds system of the main chain and the side chain of lysozyme.

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Copyright © 2006 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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