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Volume 21, Issue 5-6, Pages 245-255

Synchrotron Radiation Circular Dichroism (SRCD) spectroscopy: New beamlines and new applications in biology

Andrew J. Miles,1 Søren Vrønning Hoffmann,2 Ye Tao,3 Robert W. Janes,4 and B. A. Wallace1

1Department of Crystallography, Birkbeck College, University of London, London WC1E 7HX, UK
2Institute for Storage Ring facilities (ISA), Aarhus University, Aarhus, Denmark
3Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China
4School of Biological and Chemical Sciences, Queen Mary, University of London, London E1 4NS, UK

Copyright © 2007 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


New advances in instrumentation, demonstration of proof-of-principle studies, and development of new tools and methods for data analysis and interpretation have enabled the technique of Synchrotron Radiation Circular Dichroism (SRCD) spectroscopy to become a useful tool for structural and functional biology. This paper discusses the characterisation of two new SRCD beamlines, CD1 at the Institute for Storage Rings (ISA), Denmark and 4B8 at the Beijing Synchrotron Radiation Facility (BSRF), China, and new applications of the method for examining biological systems.