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Spectroscopy
Volume 22, Issue 1, Pages 1-19
http://dx.doi.org/10.3233/SPE-2008-0326

Raman spectroscopy: A powerful technique for biochemical analysis and diagnosis

Leonardo M. Moreira,1,2 Landulfo Silveira Jr.,1 Fábio V. Santos,1 Juliana P. Lyon,1 Rick Rocha,1 Renato A. Zângaro,1 Antonio Balbin Villaverde,1 and Marcos T. T. Pacheco1

1Instituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, São José dos Campos, São Paulo, Brazil
2Instituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, Rua Pedro Tursi, 331, 53C, Jardim satélite, CEP 12230090, São José dos Campos, São Paulo, Brazil

Copyright © 2008 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [41 citations]

The following is the list of published articles that have cited the current article.

  • Carlos Jose de Lima, Marcos Tadeu T. Pacheco, Antonio Balbin Villaverde, Renato Amaro Zangaro, Leonardo Marmo Moreira, and Alvaro Jose Damiao, “Catheter with dielectric optical filter deposited upon the fiber optic end for Raman in vivo biospectroscopy applications,” Spectroscopy-An International Journal, vol. 22, no. 6, pp. 459–466, 2008. View at Publisher · View at Google Scholar
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  • Iyandurai, and Sarojini, “Selenomethionine induced changes on the binding of spermine with DNA: A study by Fourier transform Raman and Fourier Transform infra red spectroscopy,” International Journal of Pharmacology, vol. 5, no. 2, pp. 126–136, 2009. View at Publisher · View at Google Scholar
  • Eglas Emanuel Rossi, Landulfo Silveira, Antonio Luiz Barbosa Pinheiro, Stella Regina Zamuner, Flavio Aimbire, Mauricio Maia, and Marcos Tadeu Tavares Pacheco, “Raman spectroscopy for differential diagnosis of endophthalmitis and uveitis in rabbit iris in vitro,” Experimental Eye Research, vol. 91, no. 3, pp. 362–368, 2010. View at Publisher · View at Google Scholar
  • Janaina Duarte, Marcos T. T. Pacheco, Antonio Balbin Villaverde, Rosangela Z. Machado, Renato A. Zangaro, and Landulfo Silveira, “Near-infrared Raman spectroscopy to detect anti-Toxoplasma gondii antibody in blood sera of domestic cats: quantitative analysis based on partial least-squares multivariate statistics,” Journal Of Biomedical Optics, vol. 15, no. 4, 2010. View at Publisher · View at Google Scholar
  • Fabiano Fernandes da Silva, Renato Aparecido de Souza, Marcos Tadeu Tavares Pacheco, Wellington Ribeiro, Marcos Augusto Souza Rodrigues da Silva, Humberto Miranda, Miguel Angel Castillo Salgado, Julio Cezar de Melo Castilho, and Landulfo Silveira, “Effects of Different Swimming Exercise Intensities on Bone Tissue Composition in Mice: A Raman Spectroscopy Study,” Photomedicine And Laser Surgery, vol. 29, no. 4, pp. 217–225, 2011. View at Publisher · View at Google Scholar
  • Ricardo Matias Lopes, Landulfo Silveira Jr., Marcos Augusto R.S. Silva, Kátia Ramos M. Leite, Carlos Augusto G. Pasqualucci, and Marcos Tadeu T. Pacheco, “Diagnostic model based on Raman spectra of normal, hyperplasia and prostate adenocarcinoma tissues in vitro,” Spectroscopy, vol. 25, no. 2, pp. 89–102, 2011. View at Publisher · View at Google Scholar
  • Roney Carlos Lora, Landulfo Silveira Jr., Stella Regina Zamuner, and Marcos Tadeu Tavares Pacheco, “Dispersive Raman spectroscopy for the in vitro identification and quantification of injected vancomycin intra-vitreous,” Spectroscopy, vol. 25, no. 2, pp. 103–112, 2011. View at Publisher · View at Google Scholar
  • Joo Carlos Lázaro, Alderico Rodrigues De Paula Jr. Jr., Leonardo Marmo Moreira, Juliana Pereira Lyon, Marcos Tadeu T. Pacheco, and Carlos José De Lima, “Automated diagnosis and treatment by lasers employing Raman spectroscopy and catheter with optical fibers,” Spectroscopy, vol. 25, no. 3-4, pp. 147–154, 2011. View at Publisher · View at Google Scholar
  • Humberto Miranda, Renato Aparecido De Souza, Maira Gaspar Tosato, Roberto Simão, Murilo Xavier Oliveira, Flávia Mafra De Lima, Erika Ferrari, Wellington Ribeiro, Leonardo Marmo Moreira, and Airton Abraho Martin, “Effect of different doses of creatine on the bone in thirty days of supplementation in mice: FT-Raman study,” Spectroscopy, vol. 25, no. 5, pp. 225–233, 2011. View at Publisher · View at Google Scholar
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  • Augusto Marcelli, Antonio Cricenti, Wojciech M. Kwiatek, and Cyril Petibois, “Biological applications of synchrotron radiation infrared spectromicroscopy,” Biotechnology Advances, vol. 30, no. 6, pp. 1390–1404, 2012. View at Publisher · View at Google Scholar
  • Shazza Rehman, “Vibrational Spectroscopy and Cancer,” Vibrational Spectroscopy for Tissue Analysis, vol. 20124820, 2012. View at Publisher · View at Google Scholar
  • Zanyar Movasaghi, Shazza Rehman, and Ihtesham Ur Rehman, “Raman Spectroscopy Can Detect and Monitor Cancer at Cellular Level: Analysis of Resistant and Sensitive Subtypes of Testicular Cancer Cell Lines,” Applied Spectroscopy Reviews, vol. 47, no. 7, pp. 571–581, 2012. View at Publisher · View at Google Scholar
  • Viviane G. Borio, Rubens Vinha, Renata A. Nicolau, Hueder Paulo M. de Oliveira, Carlos J. de Lima, and Landulfo Silveira, “Quantitative Evaluation of Acetaminophen in Oral Solutions by Dispersive Raman Spectroscopy for Quality Control,” Spectroscopy-An International Journal, vol. 27, no. 4, pp. 215–228, 2012. View at Publisher · View at Google Scholar
  • Edlene do Carmo M. Motta, Renato A. Zangaro, and Landulfo Silveira, “Quantitative determination of the human breast milk macronutrients by near- infrared Raman spectroscopy,” Optical Diagnostics and Sensing Xii: Toward Point-Of-Care Diagnostics and D, vol. 8229, 2012. View at Publisher · View at Google Scholar
  • Feride Severcan, and Parvez I. Haris, “Introduction to vibrational spectroscopy in diagnosis and screening,” Advances in Biomedical Spectroscopy, vol. 6, pp. 1–10, 2012. View at Publisher · View at Google Scholar
  • Damla Guldag, Ozlem Bozkurt, Sreeparna Banerjee, and Feride Severcan, “Screening and diagnosis of diabetes by vibrational spectroscopy,” Advances in Biomedical Spectroscopy, vol. 6, pp. 238–271, 2012. View at Publisher · View at Google Scholar
  • Marcos T.T. Pacheco, and Leonardo M. Moreira, “Raman Spectroscopy: New Perspectives for Its Clinical Application in Diagnosis,” Photomedicine and Laser Surgery, pp. 130913071242007, 2013. View at Publisher · View at Google Scholar
  • Lei Su, Kristy L. Cloyd, Shobhit Arya, Martin A. B. Hedegaard, Joseph A. M. Steele, Daniel S. Elson, Molly M. Stevens, and George B. Hanna, “Raman spectroscopic evidence of tissue restructuring in heat-induced tissue fusion,” Journal of Biophotonics, 2013. View at Publisher · View at Google Scholar
  • Parvez I. Haris, Ceren Aksoy, Feride Severcan, and Nihal Simsek Ozek, “Progress in vibrational spectroscopy in diagnosis and screening,” Biomedical Spectroscopy and Imaging, vol. 2, no. 1, pp. 73–81, 2013. View at Publisher · View at Google Scholar
  • Erik Gallo, and Pieter Glatzel, “Valence to Core X-ray Emission Spectroscopy,” Advanced Materials, 2014. View at Publisher · View at Google Scholar
  • Landulfo Silveira, Kátia Ramos M. Leite, Fabricio Luiz Silveira, Miguel Srougi, Marcos Tadeu T. Pacheco, Renato Amaro Zângaro, and Carlos Augusto Pasqualucci, “Discrimination of prostate carcinoma from benign prostate tissue fragments in vitro by estimating the gross biochemical alterations through Raman spectroscopy,” Lasers in Medical Science, 2014. View at Publisher · View at Google Scholar
  • Zuanfang Li, Chao Li, Duo Lin, Zufang Huang, Jianji Pan, Guannan Chen, Juqiang Lin, Nenrong Liu, Yun Yu, Shangyuan Feng, and Rong Chen, “Surface-enhanced Raman spectroscopy for differentiation between benign and malignant thyroid tissues,” Laser Physics Letters, vol. 11, no. 4, pp. 045602, 2014. View at Publisher · View at Google Scholar
  • Viviane Gadret Bório, Adjaci Uchôa Fernandes, and Landulfo Silveira Jr., “Characterization of an Ultraviolet Irradiation Chamber to Monitor Molecular Photodegradation by Raman Spectroscopy,” Instrumentation Science & Technology, pp. 150821085319008, 2015. View at Publisher · View at Google Scholar
  • Landulfo Silveira Jr., Edlene do Carmo Martins Motta, Renato Amaro Zângaro, Marcos Tadeu Tavares Pacheco, Carlos José de Lima, and Lívia Helena Moreira, “Characterization of Nutritional Parameters in Bovine Milk by Raman Spectroscopy with Least Squares Modeling,” Instrumentation Science & Technology, pp. 150615132502006, 2015. View at Publisher · View at Google Scholar
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  • Paula Kariluce de Carvalho, Landulfo Silveira, Danillo Barbosa, Egberto Munin, Miguel Angel Castillo Salgado, and Antonio Balbin Villaverde, “Analysis of experimental tendinitis in rats treated with laser and platelet-rich plasma therapies by Raman spectroscopy and histometry,” Lasers in Medical Science, 2015. View at Publisher · View at Google Scholar
  • Silveira, Schettino, Pacheco, Zângaro, L. Silveira, G. M. Schettino, M. T. T. Pacheco, and R. A. Zangaro, “Automation of a dispersive Raman spectrometer using LabVIEW aiming in vivo diagnosis of skin cancer,” IFMBE Proceedings, vol. 51, pp. 1305–1308, 2015. View at Publisher · View at Google Scholar
  • Giuseppe Pezzotti, Tetsuya Adachi, Isabella Gasparutti, Giulio Vincini, Wenliang Zhu, Marco Boffelli, Alfredo Rondinella, Elia Marin, Hiroaki Ichioka, Toshiro Yamamoto, Yoshinori Marunaka, and Narisato Kanamura, “Vibrational monitor of early demineralization in tooth enamel after in vitro exposure to phosphoridic liquid,” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2016. View at Publisher · View at Google Scholar
  • Moises Roberto Vallejo Perez, Maria Guadalupe Galindo Mendoza, Miguel Ghebre Ramirez Elias, Francisco Javier Gonzalez, Hugo Ricardo Navarro Contreras, and Carlos Contreras Servin, “Raman Spectroscopy an Option for the Early Detection of Citrus Huanglongbing,” Applied Spectroscopy, vol. 70, no. 5, pp. 829–839, 2016. View at Publisher · View at Google Scholar
  • Cassiano Junior Saatkamp, Mauricio Liberal de Almeida, Jeyse Aliana Martins Bispo, Antonio Luiz Barbosa Pinheiro, Adriana Barrinha Fernandes, and Landulfo Silveira, “Quantifying creatinine and urea in human urine through Raman spectroscopy aiming at diagnosis of kidney disease,” Journal Of Biomedical Optics, vol. 21, no. 3, 2016. View at Publisher · View at Google Scholar
  • C. Paluszkiewicz, N. Piergies, A. Sozańska, P. Chaniecki, M. Rękas, J. Miszczyk, M. Gajda, and W.M. Kwiatek, “Vibrational microspectroscopy analysis of human lenses,” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2017. View at Publisher · View at Google Scholar
  • Landulfo Silveira, Rita de Cássia Fernandes Borges, Ricardo Scarparo Navarro, Hector Enrique Giana, Renato Amaro Zângaro, Marcos Tadeu Tavares Pacheco, and Adriana Barrinha Fernandes, “Quantifying glucose and lipid components in human serum by Raman spectroscopy and multivariate statistics,” Lasers in Medical Science, 2017. View at Publisher · View at Google Scholar
  • Antônio Luiz Barbosa Pinheiro, Luiz Guilherme Pinheiro Soares, Aparecida Maria Cordeiro Marques, Maria Cristina Teixeira Cangussú, Marcos Tadeu Tavares Pacheco, and Landulfo Silveira, “Biochemical changes on the repair of surgical bone defects grafted with biphasic synthetic micro-granular HA + β-tricalcium phosphate induced by laser and LED phototherapies and assessed by Raman spectroscopy,” Lasers in Medical Science, 2017. View at Publisher · View at Google Scholar