Journal of Spectroscopy

Journal of Spectroscopy / 2010 / Article
Special Issue

From Molecule to Tissue: XIII European Conference on the Spectroscopy of Biological Molecules, Palermo, Italy, August 28–September 2, 2009, Part 2 of 2

View this Special Issue

Open Access

Volume 24 |Article ID 259258 | https://doi.org/10.3233/SPE-2010-0449

S. Khrapunov, H. Cheng, S. Hegde, J. Blanchard, M. Brenowitz, "Unusual structural characteristics of the Mycobacterium tuberculosis pentapeptide repeat protein MfpA", Journal of Spectroscopy, vol. 24, Article ID 259258, 3 pages, 2010. https://doi.org/10.3233/SPE-2010-0449

Unusual structural characteristics of the Mycobacterium tuberculosis pentapeptide repeat protein MfpA

Abstract

The solution structure and refolding of the Mycobacterium tuberculosis pentapeptide repeat protein MfpA was explored by fluorescence and circular dichroism spectroscopy. Our results show that MfpA exists in two stable structural forms which exclusively favor dimer or oligomer formation. The structural malleability of MfpA may provide a novel target for drug discovery.

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


More related articles

 PDF Download Citation Citation
 Order printed copiesOrder
Views404
Downloads573
Citations

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.