The Application of Biophysical Techniques to Study Antimicrobial Peptides

Figure 2

The use of bacterial cells in biophysical studies. Three-dimensional orthogonal projection of Escherichia coli cell (a) nontreated or (b) treated with the AMP BP100 obtained with AFM imaging. (c) Titration of Escherichia coli cells with BP100 induces an increase in the Zeta potential and a decrease in the bacterial viability, revealing that antibacterial activity correlates with the surface membrane charge neutralization. Panels (a)–(c) adapted from [2].
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(a)
460702.fig.002b
(b)
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(c)