Spectrofluorometric Analysis of New-Generation Antidepressant Drugs in Pharmaceutical Formulations, Human Urine, and Plasma Samples

Table 2

Regression data for all the analytes.

Parameters	SER	PAR	CIT	VLF	FLX
Range (ng/μL)	5–500	10–500	5–500	10–500	10–500
Regression equation (𝑌^a)
Slope (𝑏)	16.04	7.990	14.32	3.960	3.610
Intercept (𝑐)	6.0	1.50	2.60	4.70	3.30
Correlation coefficient (𝑟^2)	0.9995	0.9990	0.9992	0.9986	0.9989
LOD^c (ng/μL)	0.018	0.035	0.016	0.063	0.084
LOQ^d (ng/μL)	0.090	0.108	0. 048	0.186	0.285

^a𝑌=𝑏𝑋+𝑐, where “𝑋” is concentration in μg/mL, and 𝑌 is an emission unit. ^cLimit of detection (LOD) =3.3×S.D/slope, ^dlimit of quantification (LOQ) =10×S.D/slope.