Spectrophotometric Determination of Thioridazine Hydrochloride in Tablets and Biological Fluids by Ion-Pair and Oxidation Reactions

Table 3

Recovery of THZ in tablets formulation using the proposed methods.

Formulation	Found^a (% of nominal amount ± RSD)
	THZ-BCG	THZ-BCP	KMnO4 + IC	KMnO4 + MO	Official method
Thiozine; 25 mg/tablet	98.69±1.66	97.93±1.72	98.92±1.51	99.92±0.78	99.88±0.901
	𝑡=2.064	𝑡=1.487	𝑡=2.046	𝑡=1.876
	𝐹=3.394	𝐹=3.644	𝐹=2.808	𝐹=1.334

^aMean value of five determinations.
Tabulated t-value at the 95% confidence level is 2.77.
Tabulated F-value at the 95% confidence level is 6.39.