Spectrophotometric Determination of Thioridazine Hydrochloride in Tablets and Biological Fluids by Ion-Pair and Oxidation Reactions
Table 5
Recovery of THZ in serum and urine (, ).
| Method | Added, μg/mL | Serum | Urine | Found, μg/mL | Recovery, % | RSD, % | Found, μg/mL | Recovery, % | RSD, % |
| BCG | 8 | 8.0605 | 100.75 | 3.8828 | 7.9145 | 98.93 | 2.8539 | 16 | 15.9593 | 99.74 | 1.7306 | 15.9395 | 99.62 | 1.2147 | 24 | 23.9661 | 99.85 | 0.8900 | 24.0289 | 100.12 | 0.8345 |
| BCP | 8 | 8.1462 | 101.82 | 2.4969 | 7.9788 | 99.73 | 1.9612 | 16 | 16.0048 | 100.03 | 0.8643 | 15.9067 | 99.41 | 0.9044 | 24 | 23.9469 | 99.77 | 0.7588 | 23.7888 | 99.12 | 1.2083 |
| KMnO4 + IC | 0.4 | 0.3999 | 99.996 | 1.633 | 0.80 | 100.00 | 1.839 | 0.8 | 0.7999 | 99.996 | 2.418 | 1.1751 | 97.93 | 2.612 | 1.6 | 1.5999 | 99.996 | 1.779 | 1.5645 | 97.78 | 2.849 |
| KMnO4 + MO | 0.8 | 0.7999 | 99.998 | 0.8563 | 0.4059 | 101.49 | 2.109 | 1.2 | 1.1999 | 99.996 | 1.927 | 0.80 | 100.00 | 1.025 | 1.6 | 1.5999 | 99.996 | 0.846 | 1.1999 | 99.99 | 0.7039 |
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