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Journal of Spectroscopy
Volume 2013, Article ID 364750, 5 pages
http://dx.doi.org/10.1155/2013/364750
Research Article

Simultaneous Estimation of Ibuprofen and Phenylephrine Hydrochloride in Bulk and Combined Dosage Form by First Derivative UV Spectrophotometry Method

P.G. Department of Pharmaceutical Sciences, Sardar Patel University, Vallabh Vidyanagar, Gujarat 388120, India

Received 29 May 2013; Accepted 24 June 2013

Academic Editor: Damien Boyer

Copyright © 2013 Mehul Patel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Martindale, The Complete Drug Reference, Pharmaceutical Press, London, UK, 33rd edition, 2002.
  2. V. E. Haikala, I. K. Heimonen, and H. J. Vuorela, “Determination of ibuprofen in ointments by reversed-phase liquid chromatography,” Journal of Pharmaceutical Sciences, vol. 80, no. 5, pp. 456–458, 1991. View at Google Scholar · View at Scopus
  3. I. Savić, G. Nikolić, and V. Banković, “Development and validation of spectrophotometric method for phenylephrine hydrochloride estimation in nasal drops formulations,” Macedonian Journal of Chemistry and Chemical Engineering, vol. 27, no. 2, pp. 149–156, 2008. View at Google Scholar · View at Scopus
  4. G. W. Schieffer and D. E. Hughes, “Simultaneous stability-indicating determination of phenylephrine hydrochloride, phenylpropanolamine hydrochloride, and guaifenesin in dosage forms by reversed-phase paired-ion high-performance liquid chromatography,” Journal of Pharmaceutical Sciences, vol. 72, no. 1, pp. 55–59, 1983. View at Google Scholar · View at Scopus
  5. R. Gondalia, R. Mashru, and P. Savaliya, “Development and validation of spectrophotometric methods for simultaneous estimation of IBUPROFEN and PARACETAMOL in soft gelatin capsule by simultaneous equation method,” International Journal of ChemTech Research, vol. 2, no. 4, pp. 1881–1885, 2010. View at Google Scholar · View at Scopus
  6. D. A. Shah, D. J. Suthar, S. L. Baldania, U. K. Chhalotiya, and K. K. Bhatt, “Development and validation of liquid chromatographic method for estimation of ibuprofen and famotidine in combined dosage form,” ISRN Analytical Chemistry, vol. 2012, Article ID 674392, 5 pages, 2012. View at Publisher · View at Google Scholar
  7. B. Tsvetkova, I. P. Pencheva, A. B. Zlatkov, and P. T. Peikov, “Development and validation of RP-HPLC method for simultaneous determination of paracetamol and ibuprofen in fixed dose combinations,” International Journal of Pharmaceutical Sciences Review and Research, vol. 16, no. 1, pp. 13–16, 2012. View at Google Scholar
  8. S. S. Chitlange, D. M. Sakarkar, S. B. Wankhede, and S. G. Wadodkar, “High performance thin layer chromatographic method for simultaneous estimation of ibuprofen and pseudoephedrine hydrochloride,” International Journal of PharmTech Research, vol. 4, no. 4, pp. 1575–1580, 2012. View at Google Scholar
  9. W. D. Sam Solomon, R. A. Kumar, P. R. Vijai Anand, R. Sivakumar, and R. Venkatnarayanan, “Derivatized HPTLC method for simultaneous estimation of glucosamine and ibuprofen in tablets,” Journal of Pharmaceutical Research and Health Care, vol. 2, no. 2, pp. 156–162, 2010. View at Google Scholar · View at Scopus
  10. M. Maithani, R. Raturi, V. Gautam et al., “Development and validation of a RP-HPLC method for the determination of chlorpheniramine maleate and phenylephrine in pharmaceutical dosage form,” International Journal of Comprehensive Pharmacy, vol. 1, no. 5, pp. 1–4, 2010. View at Google Scholar
  11. A. Marín, E. García, A. García, and C. Barbas, “Validation of a HPLC quantification of acetaminophen, phenylephrine and chlorpheniramine in pharmaceutical formulations: capsules and sachets,” Journal of Pharmaceutical and Biomedical Analysis, vol. 29, no. 4, pp. 701–714, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. I. Muszalska, M. Zajac, G. Wrobel, and M. Nogowska, “UV/VIS spectrophotometric methods for determination of caffeine and phenylephrine hydrochloride in complex pharmaceutical preparations validation of the methods,” Acta Poloniae Pharmaceutica, vol. 57, no. 4, pp. 247–252, 2000. View at Google Scholar · View at Scopus
  13. S. Sheikh and S. A. Patni, “A validated, specific stability indicating reverse phase liquid chromatographic method for the simultaneous estimation of phenylephrine HCL, betamethasone valerate & lignocaine HCL in pharmaceutical ointment,” International Journal of Scientific and Research Publications, vol. 2, no. 12, 2012. View at Google Scholar
  14. P. V. Devarajan, M. H. Adani, and A. S. Gandhi, “Simultaneous determination of lignocaine hydrochloride and phenylephrine hydrochloride by HPTLC,” Journal of Pharmaceutical and Biomedical Analysis, vol. 22, no. 4, pp. 685–690, 2000. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Wankhede, K. Lad, and S. Chitlange, “Development and validation of UV-spectrophotometric methods for simultaneous estimation of cetirizine hydrochloride and phenylephrine hydrochloride in tablets,” International Journal of Pharmaceutical Sciences and Drug Research, vol. 4, no. 3, pp. 222–226, 2012. View at Google Scholar