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Journal of Spectroscopy
Volume 2013, Article ID 471061, 5 pages
Research Article

Vibrational Investigations of Silver-Doped Hydroxyapatite with Antibacterial Properties

1National Institute of Materials Physics, 105 bis Atomistilor, P.O. Box MG 07, Magurele, 077125 Bucharest, Romania
2Universite Bordeaux, EA 4592 Géoressources & Environnement, EGID, 1 Allée F. Daguin 18, 33607 Pessac Cedex, France

Received 23 June 2012; Accepted 23 July 2012

Academic Editor: Petre Makreski

Copyright © 2013 Carmen Steluta Ciobanu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Silver-doped hydroxyapatite (Ag:HAp) was obtained by coprecipitation method. Transmission electron microscopy (TEM), infrared, and Raman analysis confirmed the development of Ag:HAp with good crystal structure. Transmission electron microscopy analysis showed an uniform ellipsoidal morphology with particles from 5 nm to 15 nm. The main vibrational bands characteristic to HAp were identified. The bands assigned to phosphate vibrational group were highlighted in infrared and Raman spectra. The most intense peak Raman spectrum is the narrow band observed at 960 cm−1. In this article Ag:HAp-NPs were also evaluated for their antimicrobial activities against gram-positive, gram-negative, and fungal strains. The specific antimicrobial activity revealed by the qualitative assay demonstrates that our compounds are interacting differently with the microbial targets.