Simple Spectrophotometric Methods for Determination of Tenofovir Fumarate and Emtricitabine in Bulk Powder and in Tablets

Table 3

Determination of TEN and EMT in laboratory-prepared mixtures using the proposed spectrophotometric methods.

Nominal value (𝜇g mL^−1)		Found ± SD^a (𝜇g mL^−1)		RSD %^b		Er %^c
TEN	EMT	TEN	EMT	TEN	EMT	TEN	EMT
10.0	20.0	10.20±0.08	20.40±0.08	0.742	0.393	2.028	2.002
10.0	30.0	10.23±0.06	30.59±0.58	0.543	1.903	2.270	1.969
20.0	10.0	20.29±0.10	10.30±0.08	0.507	0.778	1.426	3.046
30.0	10.0	30.34±0.18	10.25±0.16	0.593	1.565	1.124	2.479
30.0	20.0	30.48±0.23	20.57±0.16	0.759	0.780	1.426	2.853

aMean % found ± SD for five determinations.
^b% Relative standard deviation.
^c% Relative error.