Determination of Muscone in Rats Plasma following Oral Administration of Artificial Musk: Using of Combined Headspace Gas Chromatography-Mass Spectrometry

Table 3

Method stability of muscone in plasma.

Conditions	Concentration added (ng/mL)
	378	756	7560
Direction injection	376.2	747.13	7210.94
Room temperature for 6 h	321.97	757.46	7435
Freeze thawing	391.17	696.84	7174
4°C for 10 h	407.91	794.98	8233.1
−26°C for one week	344.53	686.77	8694.88
Accuracy range (%)	85%∼108	91∼105	95∼115