TY - JOUR A2 - Baker, Mark AU - Iconaru, S. L. AU - Prodan, A. M. AU - Turculet, C. S. AU - Beuran, M. AU - Ghita, R. V. AU - Costescu, A. AU - Groza, A. AU - Chifiriuc, M. C. AU - Chapon, P. AU - Gaiaschi, S. AU - Hristu, R. AU - Stanciu, G. A. AU - Trusca, R. AU - Ganciu, M. AU - Raita, S. M. AU - Vineticu, N. AU - Ciobanu, C. S. PY - 2016 DA - 2016/12/12 TI - Enamel Based Composite Layers Deposited on Titanium Substrate with Antifungal Activity SP - 4361051 VL - 2016 AB - The goal of this paper was to investigate the antifungal activity of Enamel layers deposited on titanium substrate (Ti-Enamel) and Enamel layers deposited on titanium substrate previously coated with a vinyl polydimethylsiloxane layer (Ti-PDMS-Enamel). The physicochemical properties were also investigated. The Candida albicans biofilm development on the obtained layers was examined after 24 h, 48 h, and 72 h by confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM) after ethidium bromide staining. A significant inhibition of the fungal adherence and biofilm development was observed on Ti-Enamel layers. The antifungal results demonstrated that the use of new Ti-Enamel composite layers could represent a promising perspective for the prevention of fungal biofilms associated implant infections. SN - 2314-4920 UR - https://doi.org/10.1155/2016/4361051 DO - 10.1155/2016/4361051 JF - Journal of Spectroscopy PB - Hindawi Publishing Corporation KW - ER -