Research Article

4-Hydroxycoumarin Derivative: N-(diphenylmethyl)-2-[(2-oxo-2H-chromen-4-yl)oxy]acetamide Interaction with Human Serum Albumin

Table 3

Binding energy and hydrogen bonding interaction of the coumarin derivative with HSA active site residues.

Compound nameHydrogen bond (D-H...A)Distance (Å)Binding energy (kJ/mol)

Coumarin derivativeN–H⋯O (LEU 185)3.0−28.32
N–H⋯O (ARG 117)2.9