Research Article

FT-IR, Laser-Raman, UV-Vis, and NMR Spectroscopic Studies of Antidiabetic Molecule Nateglinide

Table 5

The experimental and computed 1H NMR isotropic chemical shifts (with respect to TMS, all values in ppm) of nateglinide.

(in DMSO-d6)Monomer 1 (in DMSO)Monomer 2 (in DMSO) (in DMSO-d6)Manomer 1 (in DMSO)Manomer 2 (in DMSO)

12.581.761.78-H421.88-H37
8.16-H88.09-H161.681.67-H311.83-H26
8.07-H107.89-H101.661.67-H281.65-H32
7.93–7.927.95-H147.84-H141.631.61-H341.55-H29
7.24–7.367.83-H127.78-H121.511.54-H291.51-H34
7.15–7.197.80-H167.70-H81.50-H321.50-H31
7.05–7.106.92-H37.10-H31.49-H391.31-H39
6.16-H66.20-H61.351.35-H371.23-H44
4.36–4.494.55-H225.76-H221.25-H441.23-H36
3.01–3.153.48-H193.71-H201.19-H461.21-H49
2.80–2.842.93-H202.67-H191.13-H491.19-H46
2.592.17-H262.05-H401.10-H451.08-H45
2.00–2.022.15-H401.94-H420.91, 0.870.86-H480.96-H48
1.97-H361.88-H280.69, 0.700.81-H500.81-H50

R2 = 0.9932 and RMSD = 0.237831578 ppm for Monomer 1 and R2 = 0.9709 and RMSD = 0.403748 ppm for Monomer 2.