Research Article

Dynamic Variation in Hippocampal Metabolism after Acute Stress Exposure: An In Vivo Proton Magnetic Resonance Spectroscopy Study at 9.4 T

Figure 1

A flowchart of 1H-MRS data analysis: from data acquisition to metabolite quantification. (a) Mouse in the stress group was exposed to acute restraint stress physically for 2 hours in a transparent 50 mL conical tube. (b) 1H-MRS data in the hippocampus were collected at 4 consecutive time points using 9.4 T Bruker MRI. (c) Metabolites were quantified using the linear combination analysis method (LCModel) in four time points.