Estimating the Ground and Excited State Dipole Moments of Levofloxacin and Norfloxacin Drugs Using Solvatochromic Effects and Computational Work

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2">Solvent</td><td class="align_center" colspan="2">Norfloxacin</td><td class="align_center" colspan="2">Levofloxacin</td></tr><tr class="thead"><td class="align_center"><span style="width: 46.8891ptpx;"><svg height="14.8825pt" id="M41" style="vertical-align:-3.2911pt" version="1.1" viewbox="-0.0498162 -11.5914 46.8891 14.8825" width="46.8891pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M219 86C216 168 211 250 206 337C201 410 189 448 163 448C131 448 79 396 43 344L60 322C91 359 110 375 118 375S132 358 136 298C141 238 152 81 155 -12H182C242 62 331 177 390 258C435 321 451 360 451 391C450 424 432 448 408 448C390 448 372 435 366 419C362 410 362 401 366 394C373 383 376 367 376 350C376 283 262 138 221 86H219Z"></path></g><g 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275V103C377 37 368 32 306 26V0H520V26C465 32 456 38 456 101V296C456 314 455 326 453 338C491 369 529 390 565 390C628 390 653 345 653 274V107C653 36 642 32 583 26V0H797Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,32.896,-5.741)"><path d="M556 236V289H56V236H556Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,38.456,-5.741)"><path d="M389 0V32C297 38 291 46 291 118V635C234 613 175 595 109 583V556L161 554C203 552 207 547 207 497V118C207 46 201 38 110 32V0H389Z"></path></g><g transform="matrix(.013,0,0,-0.013,43.423,0)"><path d="M275 270C275 450 212 609 64 710L45 686C145 604 203 442 203 270S147 -63 45 -147L64 -170C213 -68 275 89 275 270Z"></path></g></svg></span></td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left">Chloroform</td><td class="align_center">35460.99</td><td class="align_center">24626.9</td><td class="align_center">33783.78</td><td class="align_center">22782.68</td></tr><tr><td class="align_left">Dichloromethane</td><td class="align_center">34965.03</td><td class="align_center">24812.05</td><td class="align_center">32894.74</td><td class="align_center">22373.37</td></tr><tr><td class="align_left">Isopropanol</td><td class="align_center">35087.72</td><td class="align_center">23588.8</td><td class="align_center">33222.59</td><td class="align_center">20966.12</td></tr><tr><td class="align_left">Ethanol</td><td class="align_center">35335.69</td><td class="align_center">23093.09</td><td class="align_center">33222.59</td><td class="align_center">20788.29</td></tr><tr><td class="align_left">Methanol</td><td class="align_center">35460.99</td><td class="align_center">22885.39</td><td class="align_center">33444.82</td><td class="align_center">20704.79</td></tr><tr><td class="align_left">Distilled water</td><td class="align_center">36496.35</td><td class="align_center">22727.27</td><td class="align_center">34722.22</td><td class="align_center">21415</td></tr><tr><td class="align_left">Ethyl acetate</td><td class="align_center">34722.22</td><td class="align_center">24862.36</td><td class="align_center">33444.82</td><td class="align_center">21689.15</td></tr><tr><td class="align_left">Ethyl glycol</td><td class="align_center">34602.08</td><td class="align_center">22672.07</td><td class="align_center">33898.3</td><td class="align_center">20833.33</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Peaks of the absorption and emission spectra of LVF and NRF in solvents with different polarity.</div>

Journal of Spectroscopy

tab2

Table 2

Table 2: Estimating the Ground and Excited State Dipole Moments of Levofloxacin and Norfloxacin Drugs Using Solvatochromic Effects and Computational Work 

Table 2 | Estimating the Ground and Excited State Dipole Moments of Levofloxacin and Norfloxacin Drugs Using Solvatochromic Effects and Computational Work 