Role for PKC in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells
Figure 4
Fenretinide promotes Caspase activity in leukemia cell lines. Western blot analysis was performed using antibody against PARP, Caspase 3, Caspase 8, and Caspase 9 on total lysate ( cell equivalents) from REH, RS4;11, MOLT4, and CCRF-CEM (CEM) cells treated with vehicle (lane marked V; 0.1% DMSO), 1 M fenretinide (lane marked 1), 5 M fenretinide (lane marked 5), or 10 M fenretinide (lane marked 10).