Journal of Signal Transduction / 2011 / Article / Fig 4

Review Article

Itk: The Rheostat of the T Cell Response

Figure 4

T cell differentiation and their responses to pathogens. Cartoon diagram displaying the interaction of a naïve CD4+ T cell with a dendritic cell APC leading to differentiation into T helper subsets. The development of these subsets allows for protective immunity against specific pathogens. Itk is needed to promote TH2 and TH17 differentiation.

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