Prolonged Action Potential and After depolarizations Are Not due to Changes in Potassium Currents in NOS3 Knockout Ventricular Myocytes

Figure 1

Prolonged APD90 in NOS3^−/− myocytes after β-AR stimulation. (a) Representative AP traces from WT and NOS3^−/− myocytes (control-CONT; isoproterenol-ISO). (b) Summary data (mean ± S.E.M.) of RMP in WT and NOS3^−/− myocytes. (c) Summary data (mean ± S.E.M.) of β-AR stimulated increase of APD90 in WT and NOS3^−/− myocytes. *𝑃<0.05, 𝑛=4, 7 cells.

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