Developmental and Reproductive Effects of SE5-OH: An Equol-Rich Soy-Based Ingredient

Table 8

Effects of SE5-OH administration on F₁ generation rat dam gestation and delivery parameters.

Dose (mg/kg/day)	Gestation length (days)	Number of implantation sites	Number of offspring born alive	Birth index^A (%)	Gestation index^B (%)
0	22.2±0.4	15.8±1.2	14.9±1.9	93.8±7.4	100
	𝑛=18	𝑛=18	𝑛=18	𝑛=18
200	22.2±0.4	15.8±2.5	14.0±2.3	88.9±9.2	100
	𝑛=18	𝑛=18	𝑛=18	𝑛=18
1000	22.2±0.4	13.8±4.1	12.7±3.9	88.1±22.8	94.7
	𝑛=18	𝑛=19	𝑛=19	𝑛=19
2000	22.3±0.6	12.6±4.7^∗	11.3±5.1	84.5±24.8	95.2
	𝑛=20	𝑛=21	𝑛=21	𝑛=21

^ABirth index = (number of offspring born alive divided by the number of implantations); ^Bgestation index = (number of females with live offspring divided by the number of pregnant females); 𝑛: number of dams per group.