Clastogenic Effects of Glyphosate in Bone Marrow Cells of Swiss Albino Mice

Table 2

Effects of glyphosate treatment on mitotic index and micronuclei induction in swiss albino mice.

Groups (treatment)	Mitotic index (MI) after treatment			Micronuclei induction (MNPCEs/1000PCEs) after treatment
	24 hours	48 hours	72 hours	24 hours	48 hours	72 hours
Group I	4.88±0.06	4.90±0.02	4.84±0.04	1.24±0.01	1.10±0.01	1.18±0.03
(untreated)
Group II B(a)P	2.46±0.09^#	2.12±0.01^#	1.94±0.02^#	15.46±0.03*	17.50±0.10*	18.25±0.12*
(100 mg/kg b.wt)
Group III (glyphosate	4.12±.05^#	3.84±0.04^#	3.75±0.03^#	3.87±0.02*	5.76±0.08*	6.12±0.07*
dose 25 mg/kg b.wt)
Group IV (glyphosate	3.54±0.01^#	3.16±0.03^#	3.06±0.01^#	6.86±0.04*	8.25±0.04*	8.48±0.09*
dose 50 mg/kg b.wt)

Data shows mean ± SE of 5 animals in each group.
^#𝑃<.05 represents significant decrease as compared to untreated control.
^∗𝑃<.05 represents significant increase as compared to untreated control.
MNPCEs: Micronucleated polychromatic erythrocytes;
PCEs: Polychromatic erythrocytes.