The Severity of Autism Is Associated with Toxic Metal Body Burden and Red Blood Cell Glutathione Levels

Table 5

Regression analyses of initial autism severity versus urinary metal excretion and initial glutathione. In the regression equation, the suffixes for the metals refer to the value at Baseline (B) and after the 9th ( 9) dose of DMSA in Phase 1.

	Adjusted 𝑅^2	𝑃-value	Equation	Most significant variables
ATEC	0.22	.003	24.1–6.17 HgB + 76.6 SbB + 0.593 Pb9 + 3.97 Hg9 + 0.27 As9	SbB∗∗, Pb9∗
SAS	0.36	.002	4.81 + 1.70 PbB + 4.87 TlB − 0.640 HgB + 5.48 SbB − 1.87 CdB − 0.0237 AlB − 0.114 Pb9 − 3.14 Tl9 + 6.07 Sb9	PbB∗∗
ADOS (comm. + social)	0.45	.0003	13.19–4.29 HgB + 24.1 SbB − 3.67 WB − 0.0673 AlB + 2.75 Hg9 + 6.60 W9 − 0.0539 As9 + 0.0054 Glut	HgB∗∗, SbB∗, Hg9∗, W9∗
PDD-BI (modified autism score)	0.25	.004	−131.8 + 70.4 WB − 0.789 Sn9 + 18.8 Hg9 + 255 Sb9 + 21.8 W9	Sb9∗∗, WB∗, Sn9∗

^∗∗𝑃<.01, ^∗𝑃<.05