Selective Vulnerability of the Cochlear Basal Turn to Acrylonitrile and Noise
Figure 2
Four-week postexposure
DPOAE amplitudes obtained from rats exposed to (a) the 110 dB OBN-4 kHz with or
without ACN, (b) to the 97 dB OBN-8 kHz with or without ACN, or (c) to the 97 dB
OBN-16 kHz with or without ACN (see Table 1 for details). DPOAE amplitude
measured in control and ACN alone animals were included in each of the graphs
for reference. DPgrams were obtained with the levels of the primaries and
set at 75, and with The tested frequencies ranged from 3.2 to
63 kHz (geometric mean frequencies: 2.9 to 56.3 kHz), in 0.1 octave increments.
The gray areas represent the theoretical octave-band noise frequency ranges.
Error bars: . * for
technical reasons only 4 subjects could be measured with DPOAEs in the
OBN-16 kHz and in the ACN + OBN-16 kHz groups.
