Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes
Effects of Cytochrome P450 inhibitors on the viability of hepatocytes treated with fluconazole or itraconazole. Values are mean sd of 3 separate experiments. *Significant different () when compared to controls and drug only groups. Drug = itraconazole or fluconazole; Cur = curcumin; SKF = SKF 525A.
(a) 0.1 mM Fluconazole
(b) 0.1 mM Itraconazole
(c) 1.0 mM Fluconazole
(d) 1.0 mM Itraconazole
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