Journal of Toxicology / 2009 / Article / Fig 3

Research Article

Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes

Figure 3

Effects of Cytochrome P450 inhibitors on the viability of hepatocytes treated with fluconazole or itraconazole. Values are mean   sd of 3 separate experiments. *Significant different ( ) when compared to controls and drug only groups. Drug  = itraconazole or fluconazole; Cur  = curcumin; SKF  = SKF 525A.
(a) 0.1 mM Fluconazole
(b) 0.1 mM Itraconazole
(c) 1.0 mM Fluconazole
(d) 1.0 mM Itraconazole

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