Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes
AST and ALT activities in rat hepatocytes exposed to various concentrations of itraconazole and fluconazole. a–dMeans with different superscript differ significantly (). Values are mean sd of 3 separate experiments.
(a) AST activity (Fluconazole)
(b) AST activity (Itraconazole)
(c) ALT activity (Fluconazole)
(d) ALT activity (Itraconazole)
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.