Effect of Glycine on Lead Mobilization, Lead-Induced
Oxidative Stress, and Hepatic Toxicity in Rats
Figure 5
Histological lesions in the liver of rats exposed to lead and treated with glycine 1000 mg/kg for 28 days. (a) Classic liver lobule, sinusoids, portal triads, and portal vein diameter were normal (H&E stain ×20). (b) Inflammatory cell infiltration (H&E stain ×64). (c) Regular membrane cell, heterogeneous cytoplasm (H&E stain ×64). (d) Nucleus hyperchromatic with absence of basophilic staining (H&E stain ×64). (e) Apoptotic cells in the parenchyma (TUNEL stain ×64). (f) Apoptotic cells around the central vein (TUNEL stain ×64).
