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Journal of Toxicology
Volume 2012 (2012), Article ID 237506, 11 pages
Research Article

Nicotine Contents in Some Commonly Used Toothpastes and Toothpowders: A Present Scenario

Department of Pharmacology, Delhi Institute of Pharmaceutical sciences and Research (DIPSAR), University of Delhi, Pushp Vihar, Sector 3, M.B. Road, New Delhi 110017, India

Received 30 April 2011; Revised 24 August 2011; Accepted 19 September 2011

Academic Editor: Susan Sumner

Copyright © 2012 S. S. Agrawal and R. S. Ray. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The use of tobacco products as dentifrices is still prevalent in various parts of India. Tobacco use in dentifrices is a terrible scourge which motivates continued use despite its harmful effects. Indian legislation prohibits the use of nicotine in dentifrices. Nicotine is primarily injurious to people because it is responsible for tobacco addiction and is dependence forming. The present study was motivated by an interest in examining the presence of nicotine in these dentifrices. Our earlier report indicates the presence of nicotine in toothpowders. To further curb the menace of tobacco, our team again analysed the toothpowder brands of previous years and in toothpastes as well. Eight brands of commonly used toothpastes and toothpowders were evaluated by gas chromatography-mass spectroscopy. On the whole, there are a few successes but much remains to be done. Our findings indicated the presence of nicotine in two brands of dant manjans and four brands of toothpastes. Further our finding underscores the need for stringent regulations by the regulatory authorities for preventing the addition of nicotine in these dentifrices. Hence government policy needs to be targeted towards an effective control of tobacco in these dentifrices and should be properly addressed.