Genetic Variations of Glutathione S-Transferase Influence on Blood Cadmium Concentration

Table 3

Regression coefficient for blood cadmium by GSTP1  Val105Ile and interaction between GSTP1  Val105Ile and GSTT1 and GSTM1.

Genotype	Blood cadmium
	n	𝛽(S.E.)^a	𝑃 value^b
GSTP1 Val105Ile
GSTP1 Ile/Ile	212	0.27 (0.19)	0.324
GSTP1 Ile/Val	139	0.35 (0.22)	0.296
GSTP1 Val/Val	19	0.59 (0.39)	0.034
GSTM1 and GSTP1 Val105Ile
GSTM1 +/GSTP1 Ile/Ile	96	− 0.14 (0.23)	0.462
GSTM1 +/GSTP1 Ile/Val and Val/Val	82	0.32 (0.26)	0.108
GSTM1 –/GSTP1 Ile/Ile	126	0.29 (0.17)	0.288
GSTM1 –/GSTP1 Ile/Val and Val/Val	68	0.67 (0.46)	0.044
GSTT1 and GSTP1 Val105Ile
GSTT1 +/GSTP1 Ile/Ile	121	0.20 (0.13)	0.142
GSTT1 +/GSTP1 Ile/Val and Val/Val	89	0.18 (0.21)	0.296
GSTT1 –/GSTP1 Ile/Ile	108	0.39 (0.22)	0.103
GSTT1 –/GSTP1 Ile/Val and Val/Val	52	0.72 (0.58)	0.038

^a Regression coefficients.
^b𝑃 value were obtained by linear regression after controlling for sex, age, BMI, smoking status and alcohol consumption.