Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation
Figure 7
Comparison of estimated posterior distributions for 4-hour inhalation exposure to m-xylene. Posterior distributions were estimated by updating the entire set of parameters, most influential parameters, or by fixing the measured parameters and updating the remaining most influential: (a) Curine, full parameter set, (b) Curine, most influential, (c) Curine, most influential and measured spot urine production rates and creatinine concentrations.